Personal Profile
Personal profile
Cyrielle Billon, PhD, is a professor of Pharmacology at the University of Health Sciences & Pharmacy . She received her undergraduate and post-graduate education in genetic and molecular and cellular biology from the University of Lyon, France. She received a PhD in Integrative molecular and cellular biology under Jacques Samarut from the Ecole Normale Superieur of Lyon, France. Prior to joining UHSP, Dr. Billon was a postdoctoral research fellow at Saint Louis University School of Medicine in the Department of Pharmacology and Physiology under the guidance of Dr. Thomas Burris.
Dr. Billon works on characterizing the role of synthetic ligands for nuclear receptors developed in the lab on cardiovascular, metabolic, and inflammatory disorders. Her research is to identify the functions of the orphan nuclear ERRs in muscle pathophysiology and metabolic disorders using novel synthetic ligands developed by the lab.
Education/Academic qualification
Ph.D. Genetics and Molecular Biology, Doctor of Philosophy, Institut de Génomique Fonctionnelle de Lyon, Université de Lyon, Ecole Normale Supérieure de Lyon
M.S. Genetics, Master of Science, Universite Claude Bernard Lyon 1
B.S. Molecular and Cellular Biology, Bachelor of Science, Universite Claude Bernard Lyon 1
Research Interests
- Pharmacology
- Metabolic disorders
- Exercise
- Drug discovery
- Nuclear Receptor
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Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins
Freitas-Cortez, M. A., Masrorpour, F., Jiang, H., Mahmud, I., Lu, Y., Huang, A., Duong, L. K., Wang, Q., Voss, T. A., Kettlun Leyton, C. S., Wei, B., Chan, W.-K., Lin, K., Zhang, J., Tsouko, E., Ganjoo, S., Barsoumian, H. B., Riad, T. S., Hu, Y. & Leuschner, C. & 10 others, , Jan 3 2025, In: Molecular cancer. 24, 1, p. 40Research output: Contribution to journal › Article › peer-review
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Cold exposure induces the constitutively active thermogenic receptor, GPR3, via ERRα and ERRγ
Sveidahl Johansen, O., McIntyre, R. L., Rahbani, J. F., Zhang, Q., Scholtes, C., Lagarde, D. M., Billon, C., Côté, I., Delgado-Martin, M., Tandio, D., Basse, A. L., Eury, E., Kralli, A., Burris, T. P., Giguère, V., Kazak, L. & Gerhart-Hines, Z., Oct 30 2025, (E-pub ahead of print) In: Molecular Metabolism. 103, p. 102277Research output: Contribution to journal › Article › peer-review
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A Synthetic ERR Agonist Alleviates Metabolic Syndrome
Billon, C., Schoepke, E., Avdagic, A., Chatterjee, A., Butler, A. A., Elgendy, B., Walker, J. K. & Burris, T. P., Feb 1 2024, In: Journal of Pharmacology and Experimental Therapeutics. 388, 2, p. 232-240 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function
Xu, W., Billon, C., Li, H., Wilderman, A., Qi, L., Graves, A., Rideb, J. R. D. C., Zhao, Y., Hayes, M., Yu, K., Losby, M., Hampton, C. S., Adeyemi, C. M., Hong, S. J., Nasiotis, E., Fu, C., Oh, T. G., Fan, W., Downes, M. & Welch, R. D. & 7 others, , Jan 16 2024, In: Circulation. 149, 3, p. 227-250 24 p.Research output: Contribution to journal › Article › peer-review
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The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB
Losby, M., Hayes, M., Valfort, A., Sopariwala, D. H., Sanders, R., Walker, J. K., Xu, W., Narkar, V. A., Zhang, L., Billon, C. & Burris, T. P., Sep 17 2024, In: Molecular Pharmacology. 106, 4, p. 164-172 9 p.Research output: Contribution to journal › Article › peer-review