Search results

• 2024

  A Synthetic ERR Agonist Alleviates Metabolic Syndrome

  Billon, C., Schoepke, E., Avdagic, A., Chatterjee, A., Butler, A. A., Elgendy, B., Walker, J. K. & Burris, T. P., Feb 1 2024, In: Journal of Pharmacology and Experimental Therapeutics. 388, 2, p. 232-240 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

  Xu, W., Billon, C., Li, H., Wilderman, A., Qi, L., Graves, A., Rideb, J. R. D. C., Zhao, Y., Hayes, M., Yu, K., Losby, M., Hampton, C. S., Adeyemi, C. M., Hong, S. J., Nasiotis, E., Fu, C., Oh, T. G., Fan, W., Downes, M. & Welch, R. D. & 7 others, Evans, R. M., Milosavljevic, A., Walker, J. K., Jensen, B. C., Pei, L., Burris, T. & Zhang, L., Jan 16 2024, In: Circulation. 149, 3, p. 227-250 24 p.

  Research output: Contribution to journal › Article › peer-review

• The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB

  Losby, M., Hayes, M., Valfort, A., Sopariwala, D. H., Sanders, R., Walker, J. K., Xu, W., Narkar, V. A., Zhang, L., Billon, C. & Burris, T. P., Sep 17 2024, In: Molecular Pharmacology. 106, 4, p. 164-172 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2023

  Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915

  Hampton, C. S., Sitaula, S., Billon, C., Haynes, K., Avdagic, A., Wanninayake, U., Adeyemi, C. M., Chatterjee, A., Griffett, K., Banerjee, S., Burris, S. L., Schoepke, E., Boehm, T., Bess, A., de Vera, I. M. S., Burris, T. P. & Walker, J. K., Oct 5 2023, In: European Journal of Medicinal Chemistry. 258, 115582.

  Research output: Contribution to journal › Article › peer-review

• Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney

  Wang, X. X., Myakala, K., Libby, A. E., Krawczyk, E., Panov, J., Jones, B. A., Bhasin, K., Shults, N., Qi, Y., Krausz, K. W., Zerfas, P. M., Takahashi, S., Daneshpajouhnejad, P., Titievsky, A., Taranenko, E., Billon, C., Chatterjee, A., Elgendy, B., Walker, J. K. & Albanese, C. & 7 others, Kopp, J. B., Rosenberg, A. Z., Gonzalez, F. J., Guha, U., Brodsky, L., Burris, T. P. & Levi, M., Dec 2023, In: American Journal of Pathology. 193, 12, p. 1969-1987 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023

  Burris, T. P., de Vera, I. M. S., Cote, I., Flaveny, C. A., Wanninayake, U. S., Chatterjee, A., Walker, J. K., Steinauer, N., Zhang, J., Coons, L. A., Korach, K. S., Cain, D. W., Hollenberg, A. N., Webb, P., Forrest, D., Jetten, A. M., Edwards, D. P., Grimm, S. L., Hartig, S. & Lange, C. A. & 16 others, Richer, J. K., Sartorius, C. A., Tetel, M., Billon, C., Elgendy, B., Hegazy, L., Griffett, K., Peinetti, N., Burnstein, K. L., Hughes, T. S., Sitaula, S., Stayrook, K. R., Culver, A., Murray, M. H., Finck, B. N. & Cidlowski, J. A., Nov 1 2023, In: Pharmacological Reviews. 75, 6, p. 1233-1318 86 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity

  Billon, C., Sitaula, S., Banerjee, S., Welch, R., Elgendy, B., Hegazy, L., Oh, T. G., Kazantzis, M., Chatterjee, A., Chrivia, J., Hayes, M. E., Xu, W., Hamilton, A., Huss, J. M., Zhang, L., Walker, J. K., Downes, M., Evans, R. M. & Burris, T. P., Apr 21 2023, In: ACS Chemical Biology. 18, 4, p. 756-771 16 p.

  Research output: Contribution to journal › Article › peer-review
• 2022

  Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity

  Ragab, M. A., Elagawany, M., Daabees, H., Ahmed, A. S. F., Awad, E. M., Billon, C., Elgendy, B., Abouzid, K. A. M. & Kassab, S. E., Feb 2022, In: Bioorganic Chemistry. 119, 105554.

  Research output: Contribution to journal › Article › peer-review
• 2020

  A Selective ERRα/γInverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells

  Schoepke, E., Billon, C., Haynes, K. M., Avdagic, A., Sitaula, S., Sanders, R., Adeyemi, C. M., Walker, J. K. & Burris, T. P., Sep 18 2020, In: ACS Chemical Biology. 15, 9, p. 2338-2345 8 p.

  Research output: Contribution to journal › Article › peer-review

• Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonists

  Shahien, M., Elagawany, M., Sitaula, S., Goher, S. S., Burris, S. L., Sanders, R., Avdagic, A., Billon, C., Hegazy, L., Burris, T. P. & Elgendy, B., Sep 2020, In: Bioorganic Chemistry. 102, 104079.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Rev-erbα heterozygosity produces a dose-dependent phenotypic advantage in mice

  Welch, R. D., Billon, C., Kameric, A., Burris, T. P. & Flaveny, C. A., May 2020, In: PLoS ONE. 15, 5, e0227720.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids

  Griffett, K., Bedia-Diaz, G., Hegazy, L., de Vera, I. M. S., Wanninayake, U. S., Billon, C., Koelblen, T., Wilhelm, M. L. & Burris, T. P., Oct 15 2020, In: Cell Chemical Biology. 27, 10, p. 1272-1284.e4

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2019

  Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells

  Wang, Q., Robinette, M. L., Billon, C., Collins, P. L., Bando, J. K., Fachi, J. L., Sécca, C., Porter, S. I., Saini, A., Gilfillan, S., Solt, L. A., Musiek, E. S., Oltz, E. M., Burris, T. P. & Colonna, M., Oct 4 2019, In: Science Immunology. 4, 40, eaay7501.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet

  Kreienkamp, R., Billon, C., Bedia-Diaz, G., Albert, C. J., Toth, Z., Butler, A. A., McBride-Gagyi, S., Ford, D. A., Baldan, A., Burris, T. P. & Gonzalo, S., Feb 2019, In: Aging Cell. 18, 1, e12852.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• ROR regulates the NLRP3 inflammasome

  Billon, C., Murray, M. H., Avdagic, A. & Burris, T. P., Jan 4 2019, In: Journal of Biological Chemistry. 294, 1, p. 10-19 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2018

  Adropin: An endocrine link between the biological clock and cholesterol homeostasis

  Ghoshal, S., Stevens, J. R., Billon, C., Girardet, C., Sitaula, S., Leon, A. S., Rao, D. C., Skinner, J. S., Rankinen, T., Bouchard, C., Nuñez, M. V., Stanhope, K. L., Howatt, D. A., Daugherty, A., Zhang, J., Schuelke, M., Weiss, E. P., Coffey, A. R., Bennett, B. J. & Sethupathy, P. & 3 others, Burris, T. P., Havel, P. J. & Butler, A. A., Feb 2018, In: Molecular Metabolism. 8, p. 51-64 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice

  Pourcet, B., Zecchin, M., Ferri, L., Beauchamp, J., Sitaula, S., Billon, C., Delhaye, S., Vanhoutte, J., Mayeuf-Louchart, A., Thorel, Q., Haas, J. T., Eeckhoute, J., Dombrowicz, D., Duhem, C., Boulinguiez, A., Lancel, S., Sebti, Y., Burris, T. P., Staels, B. & Duez, H. M., Apr 2018, In: Gastroenterology. 154, 5, p. 1449-1464.e20

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2017

  Metabolic characterization of a novel RORα knockout mouse model without ataxia

  Billon, C., Sitaula, S. & Burris, T. P., Jul 11 2017, In: Frontiers in Endocrinology. 8, JUL, 141.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Pharmacological inhibition of REV-ERB stimulates differentiation, inhibits turnover and reduces fibrosis in dystrophic muscle

  Welch, R. D., Billon, C., Valfort, A. C., Burris, T. P. & Flaveny, C. A., Dec 1 2017, In: Scientific Reports. 7, 1, 17142.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2016

  Inhibition of RORα/γ suppresses atherosclerosis via inhibition of both cholesterol absorption and inflammation

  Billon, C., Sitaula, S. & Burris, T. P., Oct 1 2016, In: Molecular Metabolism. 5, 10, p. 997-1005 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism

  Wang, Y., Billon, C., Walker, J. K. & Burris, T. P., Feb 17 2016, In: ACS Chemical Neuroscience. 7, 2, p. 143-148 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2015

  Characteristics of patients with late manifestation of resistance thyroid hormone syndrome: a single-center experience

  Han, R., Ye, L., Jiang, X., Zhou, X., Billon, C., Guan, W., Gauthier, K., Fang, W., Wang, W., Samarut, J. & Ning, G., Dec 1 2015, In: Endocrine. 50, 3, p. 689-697 9 p.

  Research output: Contribution to journal › Article › peer-review

• Suppression of atherosclerosis by synthetic REV-ERB agonist

  Sitaula, S., Billon, C., Kamenecka, T. M., Solt, L. A. & Burris, T. P., May 8 2015, In: Biochemical and Biophysical Research Communications. 460, 3, p. 566-571 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2014

  Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration

  Sailland, J., Tribollet, V., Forcet, C., Billon, C., Barenton, B., Carnesecchi, J., Bachmann, A., Gauthier, K. C., Yu, S., Giguère, V., Chan, F. L. & Vanacker, J. M., Oct 21 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 42, p. 15108-15113 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Fluorescent push-pull pH-responsive probes for ratiometric detection of intracellular pH

  Ipuy, M., Billon, C., Micouin, G., Samarut, J., Andraud, C. & Bretonnière, Y., Jun 14 2014, In: Organic and Biomolecular Chemistry. 12, 22, p. 3641-3648 8 p.

  Research output: Contribution to journal › Article › peer-review

• TRα protects against atherosclerosis in male mice: Identification of a novel anti-inflammatory property for TRα in mice

  Billon, C., Canaple, L., Fleury, S., Deloire, A., Beylot, M., Dombrowicz, D., Del Carmine, P., Samarut, J. & Gauthier, K., Jul 2014, In: Endocrinology. 155, 7, p. 2735-2745 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2010

  Thyroid hormone receptor β(TRβ) and liver X receptor (LXR) regulate carbohydrate-response element-binding protein (ChREBP) expression in a tissue-selective manner

  Gauthier, K., Billon, C., Bissler, M., Beylot, M., Lobaccaro, J. M., Vanacker, J. M. & Samarut, J., Sep 3 2010, In: Journal of Biological Chemistry. 285, 36, p. 28156-28163 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access