Effect of restricted conformational flexibility on the permeation of model hexapeptides across caco-2 cell monolayers

Franklin W. Okumu, Giovanni M. Pauletti, David G. Vander Velde, Teruna J. Siahaan, Ronald T. Borchardt

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)169-175
Number of pages7
JournalPharmaceutical Research
Volume14
Issue number2
DOIs
StatePublished - 1997
Externally publishedYes

ASJC Scopus Subject Areas

  • Biotechnology
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Organic Chemistry
  • Pharmacology (medical)

Keywords

  • Caco-2 cells
  • CD
  • Conformation
  • Membrane permeability
  • NMR
  • Peptide delivery

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