Esterase-sensitive cyclic prodrugs of peptides: Evaluation of a phenylpropionic acid promoiety in a model hexapeptide

Giovanni M. Pauletti; Sanjeev Gangwar; Binghe Wang; Ronald T. Borchardt

doi:10.1023/A:1012091014242

Esterase-sensitive cyclic prodrugs of peptides: Evaluation of a phenylpropionic acid promoiety in a model hexapeptide

Giovanni M. Pauletti, Sanjeev Gangwar, Binghe Wang, Ronald T. Borchardt

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	11-17
Number of pages	7
Journal	Pharmaceutical Research
Volume	14
Issue number	1
DOIs	https://doi.org/10.1023/A:1012091014242
State	Published - 1997
Externally published	Yes

ASJC Scopus Subject Areas

Biotechnology
Molecular Medicine
Pharmacology
Pharmaceutical Science
Organic Chemistry
Pharmacology (medical)

Keywords

Caco-2 cells
Chemical and enzymatic stability
Esterase-sensitive prodrug
Membrane permeability
Palmitoyl-DL-carnitine
Peptide delivery

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10.1023/A:1012091014242

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title = "Esterase-sensitive cyclic prodrugs of peptides: Evaluation of a phenylpropionic acid promoiety in a model hexapeptide",

keywords = "Caco-2 cells, Chemical and enzymatic stability, Esterase-sensitive prodrug, Membrane permeability, Palmitoyl-DL-carnitine, Peptide delivery",

author = "Pauletti, {Giovanni M.} and Sanjeev Gangwar and Binghe Wang and Borchardt, {Ronald T.}",

year = "1997",

doi = "10.1023/A:1012091014242",

language = "English",

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journal = "Pharmaceutical Research",

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T1 - Esterase-sensitive cyclic prodrugs of peptides

T2 - Evaluation of a phenylpropionic acid promoiety in a model hexapeptide

AU - Pauletti, Giovanni M.

AU - Gangwar, Sanjeev

AU - Wang, Binghe

AU - Borchardt, Ronald T.

PY - 1997

Y1 - 1997

KW - Caco-2 cells

KW - Chemical and enzymatic stability

KW - Esterase-sensitive prodrug

KW - Membrane permeability

KW - Palmitoyl-DL-carnitine

KW - Peptide delivery

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U2 - 10.1023/A:1012091014242

DO - 10.1023/A:1012091014242

M3 - Article

C2 - 9034215

AN - SCOPUS:0031041493

SN - 0724-8741

VL - 14

SP - 11

EP - 17

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 1

ER -

Esterase-sensitive cyclic prodrugs of peptides: Evaluation of a phenylpropionic acid promoiety in a model hexapeptide

ASJC Scopus Subject Areas

Keywords

Access to Document

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