MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells

Noha N. Salama, Ziping Yang, Tot Bui, Rodney J.Y. Ho

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)2293-2308
Number of pages16
JournalJournal of Pharmaceutical Sciences
Volume95
Issue number10
DOIs
StatePublished - Oct 2006
Externally publishedYes

ASJC Scopus Subject Areas

  • Pharmaceutical Science

Keywords

  • Drug transport
  • Efflux pumps
  • P-glycoprotein
  • Polymorphism
  • Single nucleotide polymorphism

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