Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

Weiyi Xu; Cyrielle Billon; Hui Li; Andrea Wilderman; Lei Qi; Andrea Graves; Jernie Rae Dela Cruz Rideb; Yuanbiao Zhao; Matthew Hayes; Keyang Yu; McKenna Losby; Carissa S. Hampton; Christiana M. Adeyemi; Seok Jae Hong; Eleni Nasiotis; Chen Fu; Tae Gyu Oh; Weiwei Fan; Michael Downes; Ryan D. Welch; Ronald M. Evans; Aleksandar Milosavljevic; John K. Walker; Brian C. Jensen; Liming Pei; Thomas Burris; Lilei Zhang

doi:10.1161/CIRCULATIONAHA.123.066542

Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

Weiyi Xu
, Cyrielle Billon
, Hui Li
, Andrea Wilderman
, Lei Qi
, Andrea Graves
, Jernie Rae Dela Cruz Rideb
, Yuanbiao Zhao
, Matthew Hayes
, Keyang Yu
, McKenna Losby
, Carissa S. Hampton
, Christiana M. Adeyemi
, Seok Jae Hong
, Eleni Nasiotis
, Chen Fu
, Tae Gyu Oh
, Weiwei Fan
, Michael Downes
, Ryan D. Welch

Ronald M. Evans, Aleksandar Milosavljevic, John K. Walker, Brian C. Jensen, Liming Pei, Thomas Burris, Lilei Zhang

Department of Molecular & Human Genetics
Baylor College of Medicine
University of Health Sciences & Pharmacy
Washington University School of Medicine in St. Louis
Department of Pharmaceutical and Administrative Sciences
Center for Clinical Pharmacology
Department of Pharmacology and Physiology
Saint Louis University School of Medicine
University of North Carolina School of Medicine
Department of Psychiatry
University of Massachusetts Medical School
University Hospitals Cleveland Medical Center
Howard Hughes Medical Institute
Biology and Chemistry Department
Blackburn College
Department of Medicine
Department of Pathology and Laboratory Medicine
Children's Hospital of Philadelphia

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	227-250
Number of pages	24
Journal	Circulation
Volume	149
Issue number	3
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.123.066542
State	Published - Jan 16 2024
Externally published	Yes

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

Keywords

heart failure
cell cycle
metabolism
Myocytes, Cardiac/metabolism
Fatty Acids/metabolism
Animals
Mitochondria/metabolism
Heart Failure
Mice
Cardiomegaly/metabolism
Receptors, Estrogen/genetics

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10.1161/CIRCULATIONAHA.123.066542

Cite this

Xu, W., Billon, C., Li, H., Wilderman, A., Qi, L., Graves, A., Rideb, J. R. D. C., Zhao, Y., Hayes, M., Yu, K., Losby, M., Hampton, C. S., Adeyemi, C. M., Hong, S. J., Nasiotis, E., Fu, C., Oh, T. G., Fan, W., Downes, M., ... Zhang, L. (2024). Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function. Circulation, 149(3), 227-250. https://doi.org/10.1161/CIRCULATIONAHA.123.066542

Xu, W, Billon, C, Li, H, Wilderman, A, Qi, L, Graves, A, Rideb, JRDC, Zhao, Y, Hayes, M, Yu, K, Losby, M, Hampton, CS, Adeyemi, CM, Hong, SJ, Nasiotis, E, Fu, C, Oh, TG, Fan, W, Downes, M, Welch, RD, Evans, RM, Milosavljevic, A, Walker, JK, Jensen, BC, Pei, L, Burris, T & Zhang, L 2024, 'Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function', Circulation, vol. 149, no. 3, pp. 227-250. https://doi.org/10.1161/CIRCULATIONAHA.123.066542

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AU - Graves, Andrea

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Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function

ASJC Scopus Subject Areas

Keywords

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