Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives

Natalie D. Eddington; Donna S. Cox; Manoj Khurana; Noha N. Salama; James P. Stables; Sylvia J. Harrison; Abraham Negussie; Robert S. Taylor; Uy Q. Tran; Jacqueline A. Moore; Judith C. Barrow; K. R. Scott

doi:10.1016/S0223-5234(02)00006-5

Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives

Natalie D. Eddington
, Donna S. Cox
, Manoj Khurana
, Noha N. Salama
, James P. Stables
, Sylvia J. Harrison
, Abraham Negussie
, Robert S. Taylor
, Uy Q. Tran
, Jacqueline A. Moore
, Judith C. Barrow
, K. R. Scott

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	49-64
Number of pages	16
Journal	European Journal of Medicinal Chemistry
Volume	38
Issue number	1
DOIs	https://doi.org/10.1016/S0223-5234(02)00006-5
State	Published - Mar 2003
Externally published	Yes

ASJC Scopus Subject Areas

Pharmacology
Drug Discovery
Organic Chemistry

Keywords

Anticonvulsant activity
Enaminones
LC/MS analysis
Maximal electroshock seizure test
Structure-activity relationship

Access to Document

10.1016/S0223-5234(02)00006-5

Cite this

Eddington, N. D., Cox, D. S., Khurana, M., Salama, N. N., Stables, J. P., Harrison, S. J., Negussie, A., Taylor, R. S., Tran, U. Q., Moore, J. A., Barrow, J. C., & Scott, K. R. (2003). Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives. European Journal of Medicinal Chemistry, 38(1), 49-64. https://doi.org/10.1016/S0223-5234(02)00006-5

Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives. / Eddington, Natalie D.; Cox, Donna S.; Khurana, Manoj et al.
In: European Journal of Medicinal Chemistry, Vol. 38, No. 1, 03.2003, p. 49-64.

Research output: Contribution to journal › Article › peer-review

Eddington, ND, Cox, DS, Khurana, M, Salama, NN, Stables, JP, Harrison, SJ, Negussie, A, Taylor, RS, Tran, UQ, Moore, JA, Barrow, JC & Scott, KR 2003, 'Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives', European Journal of Medicinal Chemistry, vol. 38, no. 1, pp. 49-64. https://doi.org/10.1016/S0223-5234(02)00006-5

Eddington ND, Cox DS, Khurana M, Salama NN, Stables JP, Harrison SJ et al. Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives. European Journal of Medicinal Chemistry. 2003 Mar;38(1):49-64. doi: 10.1016/S0223-5234(02)00006-5

Eddington, Natalie D. ; Cox, Donna S. ; Khurana, Manoj et al. / Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives. In: European Journal of Medicinal Chemistry. 2003 ; Vol. 38, No. 1. pp. 49-64.

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AU - Eddington, Natalie D.

AU - Cox, Donna S.

AU - Khurana, Manoj

AU - Salama, Noha N.

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AU - Negussie, Abraham

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Synthesis and anticonvulsant activity of enaminones - Part 7. Synthesis and anticonvulsant evaluation of ethyl 4-[(substituted phenyl)amino]-6-methyl-2-oxocyclohex-3-ene-1-carboxylates and their corresponding 5-methylcyclohex-2-enone derivatives

ASJC Scopus Subject Areas

Keywords

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