Synthesis and structure activity relationship of the first class of LXR inverse agonists

Bahaa Elgendy, Kristine Griffett, Lamees Hegazy, Paolo Di Fruscia, Kirby Sample, Emmalie Schoepke, Theodore M. Kamenecka, Thomas P. Burris

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number105540
JournalBioorganic Chemistry
Volume119
DOIs
StatePublished - Feb 2022
Externally publishedYes

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Biology
  • Drug Discovery
  • Organic Chemistry

Keywords

  • Anticancer
  • Chemical Probes
  • LXR inverse agonists
  • MD Simulations
  • Tertiary sulfonamides

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