Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

Cinzia Federico; Kinan Alhallak; Jennifer Sun; Kathleen Duncan; Feda Azab; Gail P. Sudlow; Pilar de la Puente; Barbara Muz; Vaishali Kapoor; Luna Zhang; Fangzheng Yuan; Matea Markovic; Joseph Kotsybar; Katherine Wasden; Nicole Guenthner; Shannon Gurley; Justin King; Daniel Kohnen; Noha N. Salama; Dinesh Thotala; Dennis E. Hallahan; Ravi Vij; John F. DiPersio; Samuel Achilefu; Abdel Kareem Azab

doi:10.1038/s41467-020-19932-1

Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

Cinzia Federico, Kinan Alhallak, Jennifer Sun, Kathleen Duncan, Feda Azab, Gail P. Sudlow, Pilar de la Puente, Barbara Muz, Vaishali Kapoor, Luna Zhang, Fangzheng Yuan, Matea Markovic, Joseph Kotsybar, Katherine Wasden, Nicole Guenthner, Shannon Gurley, Justin King, Daniel Kohnen, Noha N. Salama, Dinesh ThotalaDennis E. Hallahan, Ravi Vij, John F. DiPersio, Samuel Achilefu, Abdel Kareem Azab

Pharmaceutical and Administrative Sciences Department

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	6037
Journal	Nature Communications
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41467-020-19932-1
State	Published - Dec 2020

ASJC Scopus Subject Areas

General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Physics and Astronomy

Access to Document

10.1038/s41467-020-19932-1

Cite this

Federico, C., Alhallak, K., Sun, J., Duncan, K., Azab, F., Sudlow, G. P., de la Puente, P., Muz, B., Kapoor, V., Zhang, L., Yuan, F., Markovic, M., Kotsybar, J., Wasden, K., Guenthner, N., Gurley, S., King, J., Kohnen, D., Salama, N. N., ... Azab, A. K. (2020). Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma. Nature Communications, 11(1), Article 6037. https://doi.org/10.1038/s41467-020-19932-1

Federico, C, Alhallak, K, Sun, J, Duncan, K, Azab, F, Sudlow, GP, de la Puente, P, Muz, B, Kapoor, V, Zhang, L, Yuan, F, Markovic, M, Kotsybar, J, Wasden, K, Guenthner, N, Gurley, S, King, J, Kohnen, D, Salama, NN, Thotala, D, Hallahan, DE, Vij, R, DiPersio, JF, Achilefu, S & Azab, AK 2020, 'Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma', Nature Communications, vol. 11, no. 1, 6037. https://doi.org/10.1038/s41467-020-19932-1

@article{c7e4062e6cb545918d73ba9b0968acfb,

title = "Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma",

author = "Cinzia Federico and Kinan Alhallak and Jennifer Sun and Kathleen Duncan and Feda Azab and Sudlow, {Gail P.} and {de la Puente}, Pilar and Barbara Muz and Vaishali Kapoor and Luna Zhang and Fangzheng Yuan and Matea Markovic and Joseph Kotsybar and Katherine Wasden and Nicole Guenthner and Shannon Gurley and Justin King and Daniel Kohnen and Salama, {Noha N.} and Dinesh Thotala and Hallahan, {Dennis E.} and Ravi Vij and DiPersio, {John F.} and Samuel Achilefu and Azab, {Abdel Kareem}",

note = "Publisher Copyright: {\textcopyright} 2020, The Author(s).",

year = "2020",

month = dec,

doi = "10.1038/s41467-020-19932-1",

language = "English",

volume = "11",

journal = "Nature Communications",

issn = "2041-1723",

number = "1",

}

TY - JOUR

T1 - Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

AU - Federico, Cinzia

AU - Alhallak, Kinan

AU - Sun, Jennifer

AU - Duncan, Kathleen

AU - Azab, Feda

AU - Sudlow, Gail P.

AU - de la Puente, Pilar

AU - Muz, Barbara

AU - Kapoor, Vaishali

AU - Zhang, Luna

AU - Yuan, Fangzheng

AU - Markovic, Matea

AU - Kotsybar, Joseph

AU - Wasden, Katherine

AU - Guenthner, Nicole

AU - Gurley, Shannon

AU - King, Justin

AU - Kohnen, Daniel

AU - Salama, Noha N.

AU - Thotala, Dinesh

AU - Hallahan, Dennis E.

AU - Vij, Ravi

AU - DiPersio, John F.

AU - Achilefu, Samuel

AU - Azab, Abdel Kareem

PY - 2020/12

Y1 - 2020/12

UR - http://www.scopus.com/inward/record.url?scp=85096740244&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85096740244&partnerID=8YFLogxK

U2 - 10.1038/s41467-020-19932-1

DO - 10.1038/s41467-020-19932-1

M3 - Article

C2 - 33247158

AN - SCOPUS:85096740244

SN - 2041-1723

VL - 11

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 6037

ER -

Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma

ASJC Scopus Subject Areas

Access to Document

Other files and links

Cite this